Malignant Catarrhal Fever in East Africa II.-Observations on Wildebeest Calves at the Laboratory and Contact Transmission of the Infection to Cattle

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Plowright W.
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A wildebeest calf was reared ill captivity and infected with malignant catarrhal fever (M.C.P.) virus by the intravenous inoculation of virulent cattle blood. It developed a viraemia, detectable in calf thyroid cultures, from the 8th day to the 31st week postinoculation; no virus was detected in the blood by 37 cultural tests during the 32nd to 85th week’s p.i. The maximum titre attained was about 102 '0 T.C.D. SO per mi. of blood and there was no free vims ill the plasma. Prom the 211d to the 12th weeks of the experime17t, viraemia was continuously present and 3 bovine calves which were housed with the wildebeest acquired the injection, apparently by contagion and after incubation periods of 30, 38 and 4S days. Prom the 13th week onwards the viraemia became il1termittent and difficult to detect; bovine calves which were maintained il1 close contact with the wildebeest during this time were 110t injected.
Research In Veterinary Science, 6 (1), p. 69-83