Oxytetracycline Hydrochloride In East Coast Fever (Theileria Parva Infection)

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Date
2000
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Kenya Agricultural Research Institute
Abstract
A cure for East Coast fever of cattle has yet to be discovered. Some of the broad-spectrUIp antibiotics have some effect, however, on the causal parasite (Theileria parva). Chlortetracycline hydrochloride (Aureomycin) administered intravenously: in repeated large doses at arbitrary irregular intervals durmg the incubation period suppressed multiplication of the schizonts but allowed the development of a solid immunity (Neitz, 1953, 1,957). Cheaper forms of Aureomycin (Aurofac 2A, Aurofac D and Aurofac 10) were found subsequently to be capable of similarly suppressing East Coast fever and allowing the development of immunity if they were administered oraBy during the incubation period (Barnett, 1956, 1957; Barnett & Bailey, 1957). This method of immunization is at present being used in Uganda and T~nganyika to immunize exotic bulls for introduction into enzootic areas. A similar method, using injectable forms of Aureomycin, was used In the Belgian Congo (Jezierski, Lambelin & Lateur, 1959).
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