Differential Susceptibility to DL-a-Difluoromethylornithine in Clinical Isolates of Trypanosoma brucei rhodesiense

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Date
1990
Authors
Bacchi, C.J.
Henry, C.
Nathan,
Livingstone, T.
Valladares, G.
Saric, M.
Paul
Sayer, P. D.
Adriel
Njogu, R.
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veterinary Record
Abstract
Protozoa of the genus Trypanosoma cause debilitating disease in humans and animals in Africa. T. brucei rhodesiense, endemic throughout Central and East Africa, is one of the most virulent. It causes n'gana, a fatal wasting disease in domestic animals, and sleeping sickness in humans. The closely related T. brucei gambiense causes West African sleeping sickness, a more slowly progressing disease although also invariably fatal if not treated.
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